As Senior Analytical Scientist within our Analytical Science Research and Development group your main role is to contribute and develop our data processing, data analysis and data interpretation of mass spectrometry data for biological samples used for biomarker discovery and validation. Alongside plan and undertake experiments intrinsic to Owlstone Medical’s assay/application/ product development projects.

Key Tasks & Accountabilities

• Develop, process, analyse and evaluate quantitative GC - mass spectrometry data for untargeted and targeted metabolomics and breathomics studies. 

• Develop and review quantitative workflows and data structure to efficiently integrate and/or develop automated data processing. 

• Provide technical review of work produced by junior members within the group, provide feedback on work and act as a mentor to ensure their continual technical development. Develop, combine, and review open-source and/or commercially available software tools for enabling feature extraction and compound identification. 

• Plan and undertake experiments intrinsic to Owlstone Medical assay/application/product development projects. 

• Process, interpret and report on acquired experimental data, ensuring that findings are scientifically accurate and are disseminated to relevant Stakeholders. 

Requirements

Person Specification

Education & Training

• BS / MS / PHD, or equivalent in metabolomics, analytical chemistry, or life sciences. 

Experience / Knowledge

Essential 

• Hands on experience with common software packages for data processing of metabolomics data (e.g., XCMS, MZmine, Thermo Compound Discoverer & Chromeleon, Agilent Mass Hunter Quant and AnalyzerPro)  

• Proven experience in pre-processing and pre-treatment of GC-MS data in the context of untargeted and targeted analysis.  

• Proven experience in building QA/QC workflows for processing GC-MS data 

• Experience in writing Python code and software versioning tools (e.g. Git/Github). 

• Proven impactful collaboration within a multidisciplinary team  

• Proven effective communication and interpretation of complex experimental results to relevant stakeholders across a multiple discipline. 

Desirable  

• Experience in structural elucidation using mass spectrometry data would be an advantage. 

• Experience in writing code R and MATLAB  

• Formal education in analytical chemistry would be an advantage. 

Professional Skills

• Excellent communication  

• Influencing and negotiation  

• Team working  

• Problem solving  

Benefits

About Owlstone Medical

Owlstone Medical is on a mission to save 100,000 lives and $1.5 billion in healthcare costs through the development and application of Breath Biopsy®. This involves collecting volatile organic compounds (VOCs) and respiratory droplets from breath, which can provide information about metabolic activity and markers related to health and disease.

Breath sampling has substantial advantages for the early detection of disease and to enable precision medicine approaches to patient care. To realize these advantages, Owlstone Medical offers Research Products and Services for biomarker discovery and is developing tests in applications including cancer, liver disease, asthma, and environmental exposure. Our work includes partnerships with major organizations including AstraZeneca, GlaxoSmithKline, the Cleveland Clinic, and the NHS and our platform is in use at well over 100 clinical and academic sites worldwide.

Our leadership in breath is underpinned by our world-class and varied team, including systems engineers, clinical scientists, analytical chemists, artificial intelligence specialists and clinical trials coordinators.

The Owlstone group also commercializes a range of highly innovative products based on its proprietary FAIMS chemical sensing technology in other markets including Scientific, Industrial Process Control, Military and Homeland Defense.

We offer a relaxed, friendly, flexible and international working environment with a strong and vibrant team-spirit. You will be rewarded with a competitive salary package that includes an Employee share options scheme and private medical insurance and your work will have a clear impact on people’s lives. If you want to experience the buzz of a thriving start-up company set to succeed on a global scale, Owlstone Medical could be the place for you.

We do not accept applications from agencies outside of our preferred supplier list. If you are concerned that your application has not been received by Owlstone Medical, please contact us using

Owlstone is an equal opportunity employer, and we will consider all qualified applicants for employment without discrimination on any characteristic protected by law including but not exhaustive to; grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status.

Due to the nature of our business, all employment is subject to satisfactory references being obtained and the attainment of a Baseline Personnel Security Standard (BPSS) check. Access to selected project information requires prior additional security authorization. Access to US technical data by employees requires prior Export Control function approval. Full clearance must be satisfactorily attained against all applicable project security and US export control authorisations. Failure to meet any reference, BPSS, project-security or export-control authorisations may have an impact on successfully completing your probationary period.

Notice to agencies

Owlstone Medical Ltd politely requests no contact from recruitment agencies or media sales. We don’t accept speculative CVs from recruitment agencies nor accept the fees associated with them.